Earning the No. 1 seed gives a team a first-round bye and home-field advantage throughout the conference playoffs — two major advantages in the chase for the Lombardi.
Since 2013, six of the 13 Super Bowl winners have been the top seed in their respective conference.
Through seven weeks, the Bills and 49ers lead the oddsboard.
Let’s check out the No. 1 seed odds for both the AFC and NFC at DraftKings Sportsbook as of Oct. 29.
No. 1 Seed Odds
AFC
The Buffalo Bills have passed the Kansas City Chiefs for the best odds to get the No. 1 seed in the AFC .
Buffalo Bills: +210
Kansas City Chiefs: +250
Jacksonville Jaguars: +700
Denver Broncos: +700
Cincinnati Bengals: +700
New England Patriots: +1100
Baltimore Ravens: +1500
Pittsburgh Steelers: +3000
Cleveland Browns: +7400
Las Vegas Raiders: +25000
Houston Texans: +25000
New York Jets: +50000
Indianapolis Colts: +70000
Tennessee Titans: +100000
Miami Dolphins: +100000
Los Angeles Chargers: not listed
What to know: Last season, the Broncos earned the AFC’s No. 1 seed before falling to the Patriots in heartbreaking fashion in the AFC Championship Game. In 2023, the Ravens finished 13-4 to secure the top seed but were eliminated by Kansas City in the conference championship.
The Bills are back atop the oddsboard. Buffalo is now favored at +210 to earn the AFC’s No. 1 seed, overtaking the Chiefs after Kansas City’s blowout loss to the Seahawks last week. The Bills are chasing their first top seed since 1993.
The Chiefs, meanwhile, have slipped to +250 after Seattle held them to just three points. Sunday’s loss was the first time in Patrick Mahomes’ career that the Chiefs did not take a snap from the red zone. But despite the loss, K.C. is still 5-1 and in first place in the AFC West. Kansas City has claimed the top seed four times with Patrick Mahomes as its starter (2018, 2020, 2022 and 2024), reaching the Super Bowl in each of the last three instances.